BVS: Bayesian Variant Selection: Bayesian Model Uncertainty Techniques for Genetic Association Studies

The functions in this package focus on analyzing case-control association studies involving a group of genetic variants. In particular, we are interested in modeling the outcome variable as a function of a multivariate genetic profile using Bayesian model uncertainty and variable selection techniques. The package incorporates functions to analyze data sets involving common variants as well as extensions to model rare variants via the Bayesian Risk Index (BRI) as well as haplotypes. Finally, the package also allows the incorporation of external biological information to inform the marginal inclusion probabilities via the iBMU.

Version: 4.12.1
Depends: MASS, msm, haplo.stats, R (≥ 2.14.0)
Published: 2012-08-09
Author: Melanie Quintana
Maintainer: Melanie Quintana <maw27.wilson at gmail.com>
License: Unlimited
NeedsCompilation: no
Materials: ChangeLog
In views: Bayesian
CRAN checks: BVS results

Downloads:

Reference manual: BVS.pdf
Package source: BVS_4.12.1.tar.gz
MacOS X binary: BVS_4.12.1.tgz
Windows binary: BVS_4.12.1.zip
Old sources: BVS archive